This course focuses of various pharmacologic formulations affecting the various body systems in normal and diseased states. It also prepares students with skills for rational use of drugs acting on special organs of the eye, ear, and nose. The coverage includes the use of anti-neoplastic agents, minerals and vitamins and effects of poisons on cells, tissues, organs and the systems.
COURSE OBJECTIVES
By the end of this unit, the student should be able to:
a) Discuss the influence of drugs on different body systems
b) Identify specific drugs for the specific systems and their uses.
c) List the adverse effects, side effects and contra-indications of the drugs.
d) Identify common antimalignant therapeutic agents.
e) Explain essential micronutrients commonly used in the treatment of some diseases.
f) Identify causes and management of poisoning in health facilities and at home.
COURSE CONTENT
Drugs used to relieve pain and inflammation (Autacoids): Analgesics and antipyretics; anesthetic agents; anti-inflammatory drugs.
Drugs acting on the cardiovascular system: Cardiac stimulants and depressants, Antianginal agents, Antihypertensives, antiarrhythmic agents, vasodilators, Antilipidemics, Stimulants of blood cells, Coagulants &Anticoagulants, Glycosides.
Urinary systems: Diuretics, drugs used to alter pH of urine, Uricosuric acid agents (drugs which alter excretion of organic molecules)and other drugs used in some urinary tract disorders
Drugs acting of the digestive system: Anti-ulcer drugs, antidiarrheal, antispasmodics, laxatives and purgatives agents, emetics and anti-emetics.
Drugs used to treat respiratory disorders: Antihistamine and nasal decongestants; expectorants and antitussives; bronchodilators and other drugs.
Drugs affecting the endocrine system: Pituitary hormones and their hypothalamic releasing factors; thyroid and antithyroid drugs; estrogens and progestins; androgens; insulin, oral hypoglycemic agents and the pharmacology of the endocrine pancreas,
Drugs acting on reproductive systems: sex hormones with their receptor agonist and Agonists, Contraception and contraceptives, oxytocic, tocolytics, fertility agents, sexual stimulants.
Drugs used in pregnancy: Drugs known to produce foetal abnormalities; drugs suspected to produce foetal abnormalities; drugs which probably do not harm the foetus. Drugs used in new born infants and during breastfeeding (lactation). Immunization and Immunological agents.
Toxicology and Its Management: Poisoning; causes, preventing and management.
Drugs used on skin, and its appendages: Dermatological, ENT, Ophthalmologic agents.
Food supplements and Nutraceuticals: vitamins, Fibre and minerals;
Teaching methods
- Modified lectures
- Demonstrations
- Group discussion
- Supervised practice
Assessment
- Tests
- Course work
- Assignments
- Written examination
REFERENCES
1) Katzung, BG, Masters, SB & Trevor, AJ, (2009) Basic and Clinical Pharmacology: McGraw-Hill
2) Clayton, B.D. & Stock, Y.N. (2001). Basic pharmacology for nurses. Philadelphia: Lippincott.
3) Gatford, J.D & Anderson, R. E. 1999. Nursing calculations Edinburgh: Churchill
4) Gutierrez, K. (1999). Pharmacotherapeutics: clinical decision making in nursing: Saunders.
5) Goodman and Gilman (2005) The Pharmacological Basis of Therapeutics: McGraw-Hill
6) Rang, HP, Dale, MM, Ritter, Flower, R (2007) Rang & Dale's Pharmacology: Churchill
7) Uganda Ministry of Health (2016). Uganda Clinical Guidelines: MOH, Uganda
- Teacher: Anyase Ronald Amaza